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Mdivi | Mitochondrial division inhibitor
Mdivi (338967-87-6) is a selective inhibitor of Dnm1 GTPase (IC50=1-10 μM). Inhibits mitochondrial outer membrane permeabilization. Mdivi inhibits mitochondrial division and apoptosis. Cell permeable.
References/Citations
1) Cassidy-Stone et al. (2008), Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization; Dev. Cell, 14 193
2) Lackner et al. (2010), Small molecule inhibitors of mitochondrial division: tools that translate basic biological research into medicine; Chem. Biol., 17 578
Catalog# 10-1179
$40.00
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
CAS:
338967-87-6
Catalog Number:
10-1179
Activity:
Mitochondrial division inhibitor
Chemical Name:
3-(2,4-Dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone
Molecular Weight:
353.23
Molecular Formula:
C15H10Cl2N2O2S
Solubility:
Soluble in DMSO (up to 25 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT
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