METTL16 degrader 15a | METTL16 degrader

METTL16 Degrader 15a chemical structure

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25 mg$350.00

15a (2869880-75-9) is a METTL16 (RNA methyltransferase-like protein 16) degrader.  It reduced METTL16 protein levels and modulated the PI3K/AKT pathway.  15a inhibited the proliferation of HepG2 cells and induced apoptosis in vitro.  It also inhibited the growth of hepatocellular carcinoma xenografts in mice

References/Citations:

  1. Liu et al. (2025), A novel cinnamic acid derivative for hepatocellular carcinoma therapy by degrading METTL16 protein; Bioorg. Med. Chem. 124 118178
2869880-75-9, Compound 15a, Compound 15a METTL16, METTL16 degrader, METTL16 degrader 15a

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