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Miglitol | beta-glucosidase inhibitor / antidiabetic

Miglitol (72432-03-2) is an α-glucosidase inhibitor which induces an enhanced and prolonged release of glucagon-like peptide-1, regulating appetite and stabilizing body weight in humans1. Miglitol displays anti-atherothrombotic effect by reducing platelet activation2 and raising circulating adiponectin levels3 in patients with type 2 diabetes. Clinically useful antidiabetic agent.

References/Citations
1) Lee et al. (2002), The effects of miglitol on glucagon-like peptide-1 secretion and appetite sensations in obese type 2 diabetics; Diabetes Obes. Metab., 4 329
2) Nomura et al. (2011), Effects of miglitol in platelet-derived microparticle, adiponectin, and selectin level in patients with type 2 diabetes mellitus; Int. J. Gen. Med., 4 539
3) Yokoyama et al. (2007), Miglitol increases the adiponectin level and decreases urinary ambumin excretion in patients with type 2 diabetes mellitus; Metabolism, 56 1458

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Focus Biomolecules supplier, chemical structure of Miglitol | beta-glucosidase inhibitor / antidiabetic | CAS 72432-03-2

Catalog#  10-2332

$60.00
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CAS:
72432-03-2
Catalog Number:
10-2332
Activity:
α-glucosidase inhibitor / antidiabetic
Alternate Names:
N-(2-Hydroxyethyl)-1-deoxynojirimycin; BAY-1099
Chemical Name:
(2R,3R,4R,5S)-1-(2-Hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
Molecular Weight:
207.23
Molecular Formula:
C8H17NO5
Solubility:
Soluble in DMSO (up to 50 mg/ml with warming), or in Water (up to 60 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT (des.)
Stability:
Stable for 2 years as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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