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Mitomycin C | DNA crosslinking and damaging agent
Mitomycin C (50-07-7) is a DNA damaging and crosslinking agent. Induces apoptosis in various cell lines. Cell permeable. This product is not approved for human therapeutic use.
References/Citations
1) Tee and Proud (2000), DNA-damaging agents cause inactivation of translational regulators linked to mTOR signaling; Oncogene, 30 21 2) Park et al. (2000), Mitomycin C induces apoptosis in a caspases-dependent and Fas/CD95- independent manner in human gastric adenocarcinoma cells; Cancer Lett., 158 125
3) Merck Index 14:6215
Catalog# 10-1170-0005
$45.00
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CAS:
50-07-7
Catalog Number:
10-1170
Activity:
DNA crosslinking and damaging agent
Chemical Name:
Natural fermentation product from Streptomyces sp.
Molecular Weight:
334.33
Molecular Formula:
C15H18N4O5
Solubility:
Soluble in DMSO (up to 15 mg/ml) or in Water (up to 1 mg/ml).
Physical Properties:
Blue-violet solid
Purity:
98% by TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. Storing aqueous solutions is not recommended.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.
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