Mitoquinone mesylate (25 wt%)/ß-cyclodextrin complex | Mitochondria-targeted antioxidant

CAS:
845959-50-4 (parent MitoQ)
Catalog Number:
10-3915
Chemical Name:
10-(6’-Ubiquinonyl)decyltriphenylphosphonium mesylate
Molecular Weight:
678.82 MitoQ, 1134.98 ß-cyclodextrin
Molecular Formula:
MitoQ C37H44O4P ∙ CH3SO3 ß-cyclodextrin C42H70O3
Solubility:
Soluble in water (up to 12 mg/mL)
Physical Properties:
Orange  solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year as supplied. Solutions in water may be stored at -20°C for up to 1 month.
Shipping Code:
RT

Available Options

Size:PriceQuantity 
5 mg$80.00
25 mg$280.00

The ß-cyclodextrin complex of Mitoquinone mesylate is an easier to use, less deliquescent form of the useful mitochondrial antioxidant Mitoquinone.  Water soluble and useable for animal studies.

References/Citations:

  1. Rodriguez-Cuenca al. (2010), Consequences of long-term oral administration of the mitochlodria-targeted antioxidant MitoQ to wild-type mice; Free Radic. Biol. Med., 48 161
  2. McManus et al. (2011), The mitochondria-targeted antioxidant MitoQ prevents loss of spatial memory retention and early neuropathology in a transgenic mouse model of Alzheimer’s disease; J. Neurosci., 31 15703
  3. Mercer et al., (2012), The mitochondria-targeted antioxidant MitoQ decreases features of the metabolic syndrome in ATM±/ApoE-/- mice; Free Radic. Biol. Med., 52 841
  4. Imaiet al. (2018), Effect of mitochondrial-targeted coenzyme Q analog on pancreatic b-cell function and energetics in high fat fed obese mice; Pharmacol. Res. Perspect., 6 e00393
CAS:
845959-50-4 (parent MitoQ)
Catalog Number:
10-3915
Chemical Name:
10-(6’-Ubiquinonyl)decyltriphenylphosphonium mesylate
Molecular Weight:
678.82 MitoQ, 1134.98 ß-cyclodextrin
Molecular Formula:
MitoQ C37H44O4P ∙ CH3SO3 ß-cyclodextrin C42H70O3
Solubility:
Soluble in water (up to 12 mg/mL)
Physical Properties:
Orange  solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year as supplied. Solutions in water may be stored at -20°C for up to 1 month.
Shipping Code:
RT

Safety Data Sheet:

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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