Obesity and metabolic diseases

Obesity and other metabolic disorders (such as fatty liver disease) are closely linked to diabetes, which in turn is tightly associated with glucose and fatty acid metabolism, circadian clock, mitochondrial function, inflammation, and many others. Focus Biomolecules offers many inhibitors and other modulators of the pathways involved in these processes.

Metabolic syndrome

NASH/NAFLD

Other metabolic diseases

  • Ervogastat | DGAT2 inhibitor
    CAS:
    2186700-33-2
    Catalog Number:
    10-4459
  • PZL-A | mtDNA activator
    CAS:
    3068830-89-4
    Catalog Number:
    10-4421
  • Migalastat HCl | Galactosidase inhibitor/Pharmacological chaperone
    CAS:
    75172-81-5
    Catalog Number:
    10-2632
  • Conduritol B epoxide | Glycosidase inhibitor
    CAS:
    6090-95-5
    Catalog Number:
    10-1172
    Activity:
    β-Glycosidase inhibitor
    Alternate Names:
    CBE
    Chemical Name:
    D,L-1,2-Anhydro-myo-inositol
    Molecular Weight:
    162.14
    Molecular Formula:
    C6H10O5
    Solubility:
    Soluble in Water (up to 25 mg/ml) or in DMSO
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Compound is hygroscopic, protect from moisture. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • KY-226 | PTP1B inhibitor
    CAS:
    1621673-53-7
    Catalog Number:
    10-4004
    Activity:
    PTP1B Inhibitor
    Chemical Name:
    4-(Biphenyl-4-ylmethylsulfanylmethyl)-N-(hexane-1-sulfonyl)benzoylamide
    Molecular Weight:
    481.67
    Molecular Formula:
    C27H31NO3S2
    Solubility:
    Soluble in DMSO (>25 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    >98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT