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Product Details

ML167 | Clk4 inhibitor

ML167 (1285702-20-6) is a highly selective cell permeable inhibitor of Cdc2-like kinase 4 (Clk4) - IC50 = 136nM. It displays at least 10-fold greater selectivity over the related kinases Clk1(1.52 μM), Clk2(1.65μM), Clk3(>10μM), Dyrk1A(>10μM), and Dyrk1B(4.4 μM).

References/Citations
1) Rosenthal et al. (2010), An inhibitor of the Cdc2-like kinase 4 (Clk4); Probe Reports from the NIH Molecular Libraries Program

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Focus Biomolecules cell signaling reagent supplier, chemical structure of ML167 | Clk4 inhibitor | CAS 1285702-20-6

Catalog#  10-4543

$75.00
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CAS:
1285702-20-6
Catalog Number:
10-4543
Activity:
Clk4 inhibitor
Chemical Name:
[5-[4-[(5-Methylfuran-2-yl)methylamino]quinazolin-6-yl]furan-2-yl]methanol
Molecular Weight:
335.36
Molecular Formula:
C19H17N2O3
Solubility:
Soluble in DMSO (greater than 25 mg/ml).
Physical Properties:
White solid
Purity:
>98% by HPLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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