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Product Details

ML300 | SARS-CoV 3CL protease inhibitor

ML300 is a selective non-covalent inhibitor of SARS-CoV 3CL protease (IC50 = 4.11 µM).1,2

References/Citations

1) Turlington, et al. (2012), Non-covalent triazol-based inhibitors of the SARS main protease 3CLpro; In: Probe Reports from the NIH Molecular Libraries Program
2) Turlington et al. (2013), Discovery of N-(Benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl)carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV)3CLpro inhibitors: Identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding; Bioorg. Med. Chem. Lett. 23 6172

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Catalog#  10-4961-0010

$75.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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Catalog Number:
10-4961
Activity:
SARS-CoV 3CL protease inhibitor
Chemical Name:
N-(4-(2-(1H-Benzo[d][1,2,3]triazol-1-yl)-N-(thiophen-3-ylmethyl)acetamido)phenyl)cyclopropanecarboxamide
Molecular Weight:
431.51
Molecular Formula:
C23H21N5O2S
Solubility:
Soluble in DMSO (>25 mg/ml).
Physical Properties:
Off-white solid
Purity:
>98% by HPLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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