ML324 | JMJD2 inhibitor

CAS:
1222800-79-4
Catalog Number:
10-1455
Activity:
JMJD2 inhibitor
Chemical Name:
N-(3-(Dimethylamino)propyl)-4-(8-hydroxyquinolin-6-yl)benzamide
Molecular Weight:
349.43
Molecular Formula:
C21H23N3O2
Solubility:
Soluble in DMSO (10 mg/ml).
Physical Properties:
Off-white to pale yellow solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Shipping Code:
RT

Available Options

size :PriceQuantity 
5 mg$50.00
25 mg$180.00

ML324 (1222800-79-4) inhibits JMJD2 histone demethylases. Represses the expression of viral (HCMV and HSV-1) immediate early genes (IC50 ~ 10 μM) and abrogates infection. ML-324 represses the reactivation of HSV from the latent state in sensory neurons.1

References/Citations:

1) Liang et al. (2013), Targeting the JMJD2 histone demethylases to epigenetically control herpesvirus infection and reactivation from latency; Sci. Transl. Med., 5 167ra5

CAS:
1222800-79-4
Catalog Number:
10-1455
Activity:
JMJD2 inhibitor
Chemical Name:
N-(3-(Dimethylamino)propyl)-4-(8-hydroxyquinolin-6-yl)benzamide
Molecular Weight:
349.43
Molecular Formula:
C21H23N3O2
Solubility:
Soluble in DMSO (10 mg/ml).
Physical Properties:
Off-white to pale yellow solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee