MRL-24 | PPAR gamma partial agonist
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 5 mg | $65.00 | ||
| 25 mg | $260.00 |
MRL-24 (393794-17-7) displays high affinity for PPARγ with excellent anti-diabetic activity in mice but poor PPARγ agonist activity in transcription and adipogenesis assays. MRL-24 is highly effective (30 nM) at blocking Cdk5-mediated phosphorylation of PPARγ. Cell permeable.
References/Citations:
1) Choi et al. (2010), Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by CDK5; Nature, 466 451
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
MRL-24 (393794-17-7) displays high affinity for PPARγ with excellent anti-diabetic activity in mice but poor PPARγ agonist activity in transcription and adipogenesis assays. MRL-24 is highly effective (30 nM) at blocking Cdk5-mediated phosphorylation of PPARγ. Cell permeable.
References/Citations:
1) Choi et al. (2010), Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by CDK5; Nature, 466 451
Related products
-
AR-A 014418 | GSK-3 inhibitor
From $50.00CAS:487021-52-3Catalog Number:10-1195Activity:GSK-3 inhibitorChemical Name:N-[(4-Methoxyphenyl)methyl]-N’-(5-nitro-2-thiazolyl)ureaMolecular Weight:308.32Molecular Formula:C12H12N4O4SSolubility:Soluble in DMSO (up to 30 mg/ml).Physical Properties:Off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.Shipping Code:RT -
Troglitazone | PPARgamma agonist
From $86.00CAS:97322-87-7Catalog Number:10-1046Activity:PPARγ agonistChemical Name:(±)-5-[4-[(6-Hydroxy-2,5,7,8-tetramethylchroman-2-yl)methoxy]-benzyl]-2,4-thiazolidinedioneMolecular Weight:441.55Molecular Formula:C24H27NO5SSolubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).Physical Properties:Off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
Efaroxan HCl | α2 adrenergic antagonist
From $80.00CAS:89197-00-2Catalog Number:10-1342Activity:α2 adrenergic antagonistAlternate Names:RX 821037AChemical Name:2-Ethyl-2-(imidazolin-2-yl)-2,3-dihydrobenzofuran, hydrochlorideMolecular Weight:252.74Molecular Formula:C13H16N2O HClSolubility:Soluble in Water (up to 25 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 1 month.Shipping Code:RT
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21
Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21
Website Created by Advanta Advertising LLC.