N-Acetyl Puromycin | Down regulates SnoN and Ski expression

CAS:
22852-13-7
Catalog Number:
10-1591
Activity:
Down regulates SnoN and Ski expression
Chemical Name:
3’-[[(2S)-2-(Acetylamino)-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3’-deoxy-N,N-dimethyladenosine
Molecular Weight:
513.55
Molecular Formula:
C24H31N7O6
Solubility:
Soluble in DMSO (up to 70 mg/ml) or in DMF (up to 55 mg/ml)
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 2 months.
Shipping Code:
RT

Available Options

Size :PriceQuantity 
5 mg$65.00
25 mg$260.00

N-Acetyl Puromycin (22852-13-7) down regulates SnoN and Ski protein expression. Induces TGF-β signaling, independently of MAPK activation. Does not bind ribosomes or block protein synthesis.

References/Citations:

1) Hernandez-Damian et al. (2013), Downregulation of SnoN oncoprotein induced by antibiotics anisomycin and puromycin positively regulates transforming growth factor-β signals; Biochim. Biophys. Acta, 1830 5049

CAS:
22852-13-7
Catalog Number:
10-1591
Activity:
Down regulates SnoN and Ski expression
Chemical Name:
3’-[[(2S)-2-(Acetylamino)-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3’-deoxy-N,N-dimethyladenosine
Molecular Weight:
513.55
Molecular Formula:
C24H31N7O6
Solubility:
Soluble in DMSO (up to 70 mg/ml) or in DMF (up to 55 mg/ml)
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 2 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

20% OFF

For Postdoc
Customers!