Nafamostat mesylate (82956-11-4) is a potent and reversible serine protease inhibitor (IC50‘s range from 0.3 – 54.0 μM). Inhibits the demethylase activity of the fat mass and obesity-associated protein (FTO).1 Cell permeable. Intended for cell culture or in vivo laboratory experimentation. This product is not approved for human therapeutic use.
1) Han et al. (2019) Identification of nafamostat mesilate as an inhibitor of the fat mass and obesity-associated protein (FTO) demethylase; Chemico-Biological Interactions, 297 80