AZD-2098 | CCR4 antagonist

CAS:
566203-88-1
Catalog Number:
10-4262
Activity:
CCR4 antagonist
Chemical Names:
2,3-Dichloro-N-(3-methoxypyrazine-2-yl)benzenesulfonamide
Molecular Weight:
334.17
Molecular Formula:
C11H9Cl2N3O3S
Solubility:
Soluble in DMSO (>25 mg/ml)
Physical Properties:
Off-white/beige solid
Purity:
>98% HPLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Available Options

Size:PriceQuantity 
5 mg$50.00
25 mg$185.00

AZD-2098 (566203-88-1) is a potent, orally bioavailable antagonist of CCR4 (pIC50 = 7.8(h), 8.0(r), 8.0(m), 7.6(d)).1 Inactive at CXCR1/2, CCR1, CCR2b, CCR5, CCR7, and CCR8 @ 10 µM.

Reference:

  1. Kindon et al. (2017), Discovery of AZD-2098 and AZD-1678, Two Potent and Bioavailable CCR4 Receptor Antagonists; ACS Med. Chem. Lett. 8 981
CAS:
566203-88-1
Catalog Number:
10-4262
Activity:
CCR4 antagonist
Chemical Names:
2,3-Dichloro-N-(3-methoxypyrazine-2-yl)benzenesulfonamide
Molecular Weight:
334.17
Molecular Formula:
C11H9Cl2N3O3S
Solubility:
Soluble in DMSO (>25 mg/ml)
Physical Properties:
Off-white/beige solid
Purity:
>98% HPLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee