News & Events

Probiotics and immune checkpoint inhibitors

Journal Club: MJ Bender and coworkers at the University of Pittsburgh School of Medicine reported recently (in Cell) fascinating microbial-host crosstalk between probiotic-released aryl hydrocarbon receptor

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Pain research news

Journal Club: In a paper just out in Nature Communications, Arthur Neuberger and coworkers report the cryo-electron microscopy structures of human TRPV1 in the apo state

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Orphan Receptor GPR139

Journal Club: Lisa Pallareti and coworkers at Univ. Copenhagen reported on the pharmacological characterization of agonists and antagonists of the orphan receptor GPR139. GPR139 is predominantly

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Product Focus: WP631

A small molecule that binds DNA at one bis-intercalation site can affect binding by another moiety nearby. WP631 is a novel bis-intercalating daunomycin dimer and potent

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