News & Events

Mitophagy news

Urolithin A is a microbial metabolite of dietary ellagitannins produced in the gut. It has been shown to induce mitophagy and prolong lifespan in C. elegans

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Filipin III for Cholesterol Research

Filipin III is a microbial natural product isolated from Streptomyces filipinensis. It is an important fluorescent probe for cellular cholesterol detection. In addition, because it binds

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Sinefungin in Antiviral Research

Two recent papers employed Sinefungin in determination of the structure of two different viral methyltransferases. Sinefungin is a Streptomyces natural product analog of S-adenosylmethionine acting as

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SSRIs block SARS-CoV-2 protease in silico

In a molecular docking analysis, Tronco Pauletto et al. found that antidepressants such as fluoxetine, citalopram, and norfluoxetine likely interact with and disrupt SARS-CoV-2 main protease

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Obesity research news

Carlos Guijas and coworkers at Scripps recently found that the leukotriene antagonist and antiasthmatic agent zafirlukast was able to differentiate adipocyte precursors into functional brown adipocytes.

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