Stem Cell Viability
Focus Biomolecules
September 1, 2022
Chroman 1 is an important new small molecule tool for the generation and maintenance of stem cells. An extremely potent (1 pM) inhibitor of Rho kinase
News & Events
Epigenetics and Inflammation
Focus Biomolecules
August 25, 2022
In a recent paper in Cell Research, Li and coworkers explored the nuclear function of RIPK1 and demonstrated that RIPK1 phosphorylates a key component of the
Synthesis and Characterization of Destruxins
Focus Biomolecules
August 12, 2022
In the August issue of J. Antibiotics (Tokyo) Yoshida and coworkers at the University of Tsukuba reviewed their excellent work on synthesis, SAR, biology and chemical
Tumor immune surveillance news
Focus Biomolecules
August 1, 2022
Yan and coworkers have demonstrated a potential way to boost innate immune attack on solid tumors. They found that Rocaglamide, a structurally novel natural product, promoted
Rare enzyme activator, Mitapivat
Focus Biomolecules
July 19, 2022
Mitapivat is an allosteric activator of red blood cell pyruvate kinase, the enzyme that performs the final step of glycolysis: it catalyzes the conversion of phosphoenolpyruvate
Cancer Metabolism research tools
Focus Biomolecules
July 14, 2022
Cancer cells modify their metabolism in order to survive and grow. For example, they employ the Warburg effect (increasing glucose uptake and directly converting it to
