Focus will be exhibiting at AACR, April 16-19 in Orlando, FL. Stop by our booth #3242 and chat with our scientists! Learn about our new cutting-edge
A small molecule that binds DNA at one bis-intercalation site can affect binding by another moiety nearby. WP631 is a novel bis-intercalating daunomycin dimer and potent
New Product Focus: Chroman 1 is an important new small molecule tool for the generation and maintenance of stem cells. An extremely potent (1 pM) inhibitor
Journal Club: Surfactin is a cyclic lipopeptide microbial metabolite produced by Bacillus subtilis that acts as a biosurfactant among other interesting activities. S.C. Yang and coworkers
In The News: Bempedoic acid is an FDA-approved drug for the treatment of hypercholesterolemia sold under the brand name Nexletol. It is an ATP citrate lyase
Focus on Drug Discovery: Saridegib is a natural product-inspired drug candidate. Its prototype, cyclopamine was discovered as a teratogenic steroidal alkaloid that was found to cause
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