Nimodipine | L-type calcium channel blocker
NMR (Conforms)
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 100 mg | $50.00 | ||
| 500 mg | $180.00 |
Nimodipine (66085-59-4) is an L-type calcium channel blocker.1 Prevents age-induced learning deficits in a rat model.2 Facilitates recovery of function after brain damage3 and displays neuroprotective effects4. Promotes remyelination in a mouse model of multiple sclerosis.5 In clinical use for reduction of cerebral vasospasm following subarachnoid hemorrhage.6
References/Citations:
1) Cohen and McCarthy (1987), Nimodipine block of calcium channels in rat anterior pituitary cells; J. Physiol., 387 195
2) Batuecas et al. (1998), Effects of chronic nimodipine on working memory of old rats in relation to defects in synaptosomal calcium homeostasis; Eur. J. Pharmacol., 350 141
3) LeVere et al. (1989), Recovery of function after brain damage: facilitation by the calcium entry blocker nimodipine; Behav. Neurosci., 103 561
4) Herzfeld et al. (2014), Investigation of the neuroprotective impact of nimodipine on Neuro2a cells by means of a surgery-like stress model; Int. J. Mol. Sci., 15 18453
5) Schampel et al. (2017), Nimodipine fosters remyelination in a mouse model of multiple sclerosis and induces microglia-specific apoptosis; Proc. Natl. Acad. Sci. USA, 114 E3295
6) Allen et al. (1983), Cerebral arterial spasm – a controlled trial of nimodipine in patients with subarachnoid hemorrhage; N. England J. Med., 308 619
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Nimodipine (66085-59-4) is an L-type calcium channel blocker.1 Prevents age-induced learning deficits in a rat model.2 Facilitates recovery of function after brain damage3 and displays neuroprotective effects4. Promotes remyelination in a mouse model of multiple sclerosis.5 In clinical use for reduction of cerebral vasospasm following subarachnoid hemorrhage.6
References/Citations:
1) Cohen and McCarthy (1987), Nimodipine block of calcium channels in rat anterior pituitary cells; J. Physiol., 387 195
2) Batuecas et al. (1998), Effects of chronic nimodipine on working memory of old rats in relation to defects in synaptosomal calcium homeostasis; Eur. J. Pharmacol., 350 141
3) LeVere et al. (1989), Recovery of function after brain damage: facilitation by the calcium entry blocker nimodipine; Behav. Neurosci., 103 561
4) Herzfeld et al. (2014), Investigation of the neuroprotective impact of nimodipine on Neuro2a cells by means of a surgery-like stress model; Int. J. Mol. Sci., 15 18453
5) Schampel et al. (2017), Nimodipine fosters remyelination in a mouse model of multiple sclerosis and induces microglia-specific apoptosis; Proc. Natl. Acad. Sci. USA, 114 E3295
6) Allen et al. (1983), Cerebral arterial spasm – a controlled trial of nimodipine in patients with subarachnoid hemorrhage; N. England J. Med., 308 619
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