OAC2 | Enhances stem cell reprogramming

Available Options

Size:PriceQuantity 
5 mg$45.00
25 mg$175.00
Request Quote / Bulk / Custom Size
Product Inquiry

OAC2 (Oct4 Activating Compound 2; 6019-39-2) is an activator of octamer-binding transcription factor 4 (Oct4) which plays a role in self-renewal of undifferentiated embryonic stem cells and regulates embryonic stem cell pluripotency. Thus, OAC2 enhances iPSC reprogramming efficiency.1  OAC2 is one component in the 9C cocktail used to convert human fibroblasts to functional cardiomyocytes.2 It has been employed in the generation of chicken induced pluripotent stem cells from somatic cells using multi-lentiviral transduction.3

References/Citations:

  1. Li et al. (2012), Identification of Oct4-activating compounds that enhance reprogramming efficiency; Proc. Natl. Acad. Sci. USA 109 20853
  2. Cao et al. (2016), Conversion of human fibroblasts into functional cardiomyocytes by small molecules; Science 352 1216
  3. Liu et al. (2025), Generation of chicken induced pluripotent stem cells (iPSCs) from somatic cells using multi-lentiviral transduction and OAC2; Theriogenology 247 117567
6019-39-2, OAC2, OAC2 supplier, Oct4 activator

Safety Data Sheet:

N/A

Product Data Sheet:

Download Product Data Sheet

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

OAC2 (Oct4 Activating Compound 2; 6019-39-2) is an activator of octamer-binding transcription factor 4 (Oct4) which plays a role in self-renewal of undifferentiated embryonic stem cells and regulates embryonic stem cell pluripotency. Thus, OAC2 enhances iPSC reprogramming efficiency.1  OAC2 is one component in the 9C cocktail used to convert human fibroblasts to functional cardiomyocytes.2 It has been employed in the generation of chicken induced pluripotent stem cells from somatic cells using multi-lentiviral transduction.3

References/Citations:

  1. Li et al. (2012), Identification of Oct4-activating compounds that enhance reprogramming efficiency; Proc. Natl. Acad. Sci. USA 109 20853
  2. Cao et al. (2016), Conversion of human fibroblasts into functional cardiomyocytes by small molecules; Science 352 1216
  3. Liu et al. (2025), Generation of chicken induced pluripotent stem cells (iPSCs) from somatic cells using multi-lentiviral transduction and OAC2; Theriogenology 247 117567