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Product Details

Optovin | TRPA1 channel activator

Optovin (348575-88-2) is a reversible photoactive TRPA1 activator. Optovin stimulates human TRPA1 channels and enables repeated photoactivation of motor behaviors in wild-type zebrafish (EC50 = 2 μM) and mice, in vivo. Photodetection is performed by sensory neurons expressing the TRPA1 cation channel which is activated via structure-dependent photochemical reactions with redox-sensitive cysteine residues.1

References/Citations

1) Kokel et al. (2013), Photochemical activation of TRPA1 channels in neurons and animals; Nat. Chem. Biol., 9 257

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Focus Biomolecules cell signaling reagent supplier, chemical structure Optovin | TRPA1 channel activator | CAS 348575-88-2

Catalog#  10-1456-0005

$70.00
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Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
348575-88-2
Catalog Number:
10-1456
Activity:
TRPA1 channel activator
Chemical Name:
5-[[2,5-Dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-2-thioxo-4-thiazolidinone
Molecular Weight:
315.41
Molecular Formula:
C185/sub>H13N3OS2
Solubility:
Soluble in DMSO (up to 30 mg/ml)
Physical Properties:
Tan solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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