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Product Details

Oseltamivir Phosphate | Neuraminidase inhibitor / Antiviral

Oseltamivir phosphate (204255-11-9) is a potent viral neuraminidase inhibitor and a clinically useful treatment for influenzas A and B.1,2 Oseltamivir is a prodrug that is converted to the active acid in vivo – IC50 for active acid in vitro = 2 nM.3

References/Citations
1) Sidwell et al. (1998), Inhibition of influenza virus infections in mice by GS4104, an orally effective influenza virus neuraminidase inhibitor; Antiviral Res., 37 107
2) McClellan and Perry (2001), Oseltamivir: A Review of Its Use in Influenza; Drugs, 61 263
3) Li et al. (1998), Identification of GS4104 as an orally bioavailable prodrug of the influenza virus neuraminidase inhibitor GS4071; Antimicrob. Agents Chemother., 42 647

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Catalog#  10-4483-0050

$30.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
204255-11-9
Catalog Number:
10-4483
Activity:
Neuraminidase inhibitor / Antiviral
Chemical Name:
Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-pentan-3-yloxycyclohexene-1-carboxylate phosphoric acid salt
Alternate Name:
GS4104; Tamiflu
Molecular Weight:
410.40
Molecular Formula:
C16H28N2O4 • H3PO4
Solubility:
Soluble in DMSO (up to 40 mg/ml) or in Water (up to at least 40 mg/ml).
Physical Properties:
White solid
Purity:
99% by HPLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 1 year as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

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