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Ouabain | Na+/K+ ATPase inhibitor

Ouabain (11018-89-6) is a selective inhibitor of Na+ K+-ATPase isolated from Strophanthus gratus1. Endogenous ouabain is found in human circulation2. Displays cardiotonic and diuretic activity. May be used to induce hypertensive rat model3. Cell permeable and active in vivo.

References/Citations
1) Silva et al. (2012), New insights into the regulation of Na+,K(+)-ATPase by ouabain; Int. Rev. Cell. Mol. Biol., 294 99
2) Dvela et al. (2012), Endogenous ouabain regulates cell viability; Am. J. Physiol. Cell, Physiol., 302 C442

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Ouabain | 11018-89-6 | Structure | Supplier

Catalog#  10-1248

$25.00
Quantity
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CAS:
11018-89-6
Catalog Number:
10-1248
Activity:
Na+/K+ ATPase inhibitor
Chemical Name:
3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-1,5,11_,14,19-pentahydoxycard-20(22)-enolide octahydrate
Molecular Weight:
728.79
Molecular Formula:
C29H44O12 8(H2O)
Solubility:
Soluble in DMSO (up to 50 mg/ml), or in Water (up to 10 mg/ml).
Physical Properties:
White solid
Purity:
99% by TLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 2 years as supplied. Protect from exposure to moisture. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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