Pepstatin A | Aspartic protease inhibitor
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 5 mg | $32.00 | ||
| 25 mg | $100.00 |
Pepstatin A (26305-03-3) is a selective inhibitor of aspartyl proteases.1 Inhibits human pepsin, human gastricsin, renin, cathepsin D and E and bovine chymosin.2 Does not inhibit thiol proteases, neutral proteases or serine proteases.3 Pepstatin A suppresses RANKL-induced osteoclast differentiation.4
References/Citations:
1) Merck Index 14:7147
2) Marciniszyn et al. (1976) Mode of inhibition of acid proteases by pepstatin; J. Biol. Chem., 251 7088
3) Oda (2012) New families of carboxy peptidases: serine-carboxyl peptidases and glutamic peptidases; J. Biochem., 151 13
4) Yoshida et al. (2006) Pepstatin A, an aspartic proteinase inhibitor, suppresses RANKL-induced osteoclast differentiation; J. Biochem., 139 583
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Pepstatin A (26305-03-3) is a selective inhibitor of aspartyl proteases.1 Inhibits human pepsin, human gastricsin, renin, cathepsin D and E and bovine chymosin.2 Does not inhibit thiol proteases, neutral proteases or serine proteases.3 Pepstatin A suppresses RANKL-induced osteoclast differentiation.4
References/Citations:
1) Merck Index 14:7147
2) Marciniszyn et al. (1976) Mode of inhibition of acid proteases by pepstatin; J. Biol. Chem., 251 7088
3) Oda (2012) New families of carboxy peptidases: serine-carboxyl peptidases and glutamic peptidases; J. Biochem., 151 13
4) Yoshida et al. (2006) Pepstatin A, an aspartic proteinase inhibitor, suppresses RANKL-induced osteoclast differentiation; J. Biochem., 139 583
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1-855-FOCUS21
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