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Phorbol 12-myristate-13-acetate | PKC activator

Phorbol 12-myristate-13-acetate (16561-29-8) activates protein kinase C (10-100 ng/ml)1. May display PKC-independent effects in various cell types2. Warning: Phorbol 12-myristate-13-acetate is a skin irritant. Avoid contact with this compound.

References/Citations
1) Saraiva et al. (2004), Characterization of phorbol esters activity on individual mammalian protein kinase C isoforms, using the yeast phenotypic assay; Eur. J. Pharmacol., 491 101
2) Doerner et al. (1990), Protein kinase C-dependent and independent effects of phorbol esters on hippocampal calcium channel current; J. Neurosci., 10 1699
3) Merck Index 14:7332

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Focus Biomolecules supplier, chemical structure of Phorbol 12-myristate-13-acetate | PKC activator | CAS 16561-29-8

Catalog#  10-2165

$30.00
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CAS:
16561-29-8
Catalog Number:
10-2165
Activity:
PKC activator
Alternate Names:
PMA, TPA
Chemical Name:
12-O-Tetradecanoylphorbol-13-acetate
Molecular Weight:
616.84
Molecular Formula:
C36H56O8
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
Physical Properties:
Colorless oil
Purity:
99% by HPLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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