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Product Details

PNU 74654 | Wnt pathway blocker

PNU-75654 (113906-27-7) disrupts the Wnt signaling pathway via inhibition of the interaction (KD50 = 450 nM) between β-catenin and T cell factor 4 (Tcf4).

References/Citations
1) Trosset et al. (2006) Inhibition of protein-protein interactions: the discovery of druglike beta-catenin inhibitors by combining virtual and biophysical screening; Proteins, 64 60

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Catalog#  10-4519

$60.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
113906-27-7
Catalog Number:
10-4519
Activity:
Wnt pathway blocker
Chemical Name:
2-Phenoxybenzoic acid [(5-methyl-2-furanyl)methylene]hydrazide
Molecular Weight:
320.35
Molecular Formula:
C19H16N2O3
Solubility:
Soluble in DMSO (up to 25 mg/ml).
Physical Properties:
Off-white solid
Purity:
>98% by TLC
Storage Temperature:
-20°
Stability:
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

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