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Pterostilbene | Resveratrol analog

Pterostilbene (537-42-8) is a naturally occurring stilbenoid related to resveratrol (Cat.# 10-1057). Displays antiproliferative activity. Induces accumulation of autophagic vacuoles followed by cell death in HL60 cells1. Pterostilbene displays protective effects against free radical-mediated oxidative damage2. Produces anti-inflammatory effects by down-regulating the activity of TNFα3. Activates AMPK4.

References/Citations
1) Siedlecka-Kroplewska et al. (2013), Pterostilbene induces accumulation of autophagic vacuoles followed by cell death in HL60 human leukemia cells; J. Physiol. Phamracol., 64 545
2) Acharya et al. (2013), Protective effect of Pterostilbene against free radical mediated oxidative damage; BMC Complernt Altern. Med., 13 238
3) McCormack et al. (2012), Pterostilbene ameliorates tumor necrosis factor alpha-induced pancreatitis in vitro; Infect. J. Surg. Res., 178 28
4) Lin et al. (2012), Activation of AMPK by pterostilbene suppresses lipogensis and cell-cycle progression in p53 positive and negative human prostate cancer cells; J. Agric. Food Chem., 60 6399

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Catalog#  10-2367

$60.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
537-42-8
Catalog Number:
10-2367
Activity:
Resveratrol analog
Alternate Names:
4-[(1E)-2-(3,5-Dimethoxyphenyl)ethyl]phenol
Chemical Name:
3,5-Dimethoxy-4'-hydroxystilbene
Molecular Weight:
256.28
Molecular Formula:
C16H16O3
Solubility:
Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 50 mg/ml).
Physical Properties:
White or off-white solid
Purity:
98% by HPLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 week.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

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