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Product Details

Punicalagin | Anti inflammatory

Punicalagin (65995-63-3) is a polyphenolic compound isolated from pomegranates possessing antioxidant, anti-inflammatory, and antitumorigenic properties.1,2 It has been shown to reduce high glucose-induced neural tube defects by blocking cellular stress and caspase activation.3 Punicalagin prevented high-fat diet induced obesity associated accumulation of cardiac triglyceride and cholesterol as well as myocardial damage via AMPK mediated modulation of mitochondria and phase II enzymes.4

References/Citations
1) Seeram et al. (2005), In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice; J. Nutr. Biochem., 16 360
2) Adams et al. (2006), Pomegranate Juice, Total Pomegranate Ellagitannins, and Punicalagin Suppress Inflammatory Cell Signaling in Colon Cancer Cells; J. Agric. Food Chem., 54 980
3) Zhong et al. (2015), Punicalagin exerts protective effect against high glucose-induced cellular stress and neural tube defects; Biochem. Biophys. Res. Commun., 467 179
4) Cao et al. (2015), Punicalagin, an active component in pomegranate, ameliorates cardiac mitochondrial impairment in obese rats via AMPK activation; Sci. Rep., 5 14014

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Catalog#  10-4583

$50.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
65995-63-3
Catalog Number:
10-4583
Activity:
Anti-inflammatory / antioxidant / anti-tumor agent
Molecular Weight:
1084.72
Molecular Formula:
C48H28O30
Solubility:
Soluble in Water (greater than 20 mg/ml)
Physical Properties:
Yellow solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 1 year as supplied. Solutions in distilled water may be stored at -20° for up to 2 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

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