Inhibitors

  • SBI-0206965 | ULK1 inhibitor

    CAS:
    1884220-36-3
    Catalog Number:
    10-1623
    Activity:
    ULK1 inhibitor
    Chemical Name:
    2-((5-Bromo-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)oxy)-N-methylbenzamide
    Molecular Weight:
    489.32
    Molecular Formula:
    C21H21BrN4O4
    Solubility:
    Soluble in DMSO (up to 30 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC/TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $65.00
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  • Spautin-1 | Inhibits autophagy by inhibiting USP 10 and 13

    CAS:
    1262888-28-7
    Catalog Number:
    10-1367
    Activity:
    Inhibits autophagy by inhibiting USP 10 and 13
    Chemical Name:
    6-Fluoro-N[(4-fluorophenyl)methyl]-4-quinazolinamine
    Molecular Weight:
    271.27
    Molecular Formula:
    C15H11F2N3
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 15 mg/ml with warming).
    Physical Properties:
    Tan solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $65.00
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  • Vacuolin-1 | Autophagy/PIKfyve inhibitor

    CAS:
    351986-85-1
    Catalog Number:
    10-5151
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  • Vinblastine sulfate | Microtubule depolymerizer

    CAS:
    143-67-9
    Catalog Number:
    10-2050
    Activity:
    Microtubule depolymerizer
    Alternate Names:
    Vincaleukoblastine
    Molecular Weight:
    909.08
    Molecular Formula:
    C46H58N4O9 H2SO4
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Water (up to 50 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Stability:
    Store for up to 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $48.00
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  • Wortmannin | PI3K inhibitor

    CAS:
    19545-26-7
    Catalog Number:
    10-2115
    Activity:
    PI3K inhibitor
    Chemical Name:
    [(1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-6,11,16-trioxo-13,17-dioxapentacyclo[10.6.1.02,10.05,9.015,19]nonadeca-2(10),12(19),14-trien-3-yl] acetate
    Molecular Weight:
    428.44
    Molecular Formula:
    C23H24O8
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Dried aliquots evaporated from ethanol may be stored at -20° for several months. Solutions however are not stable and must be used within one working day. Note: Wortmannin decomposes fairly quickly in culture media
    Shipping Code:
    RT
    From $42.00
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