Inhibitors

  • Rotenone | Mitochondrial Complex I Inhibitor

    CAS:
    83-79-4
    Catalog Number:
    10-2277
    Activity:
    Mitochondrial Complex I Inhibitor
    Chemical Names:
    (2R,6aS,12aS)-1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one
    Alternate Name:
    NSC-26285; Nicouline
    Molecular Weight:
    394.42
    Molecular Formula:
    C23H22O6
    Solubility:
    Soluble in DMSO (50 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    Room Temperature
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $48.00
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  • SBI-0206965 | ULK1 inhibitor

    CAS:
    1884220-36-3
    Catalog Number:
    10-1623
    Activity:
    ULK1 inhibitor
    Chemical Name:
    2-((5-Bromo-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)oxy)-N-methylbenzamide
    Molecular Weight:
    489.32
    Molecular Formula:
    C21H21BrN4O4
    Solubility:
    Soluble in DMSO (up to 30 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC/TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $65.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • SHP099 | SHP2 inhibitor

    CAS:
    1801747-11-4
    Catalog Number:
    10-4604
    Activity:
    SHP2 inhibitor
    Chemical Name:
    6-(4-Amino-4-methylpiperidin-1-yl)-3-(2,3-dichlorophenyl)pyrazin-2-amine dihydrochloride
    Molecular Weight:
    425.18
    Molecular Formula:
    C16H19Cl2N5 • 2HCl
    Solubility:
    Soluble in DMSO (up to 5 mg/ml) or in water (up to at least 20 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $75.00
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  • Spautin-1 | Inhibits autophagy by inhibiting USP 10 and 13

    CAS:
    1262888-28-7
    Catalog Number:
    10-1367
    Activity:
    Inhibits autophagy by inhibiting USP 10 and 13
    Chemical Name:
    6-Fluoro-N[(4-fluorophenyl)methyl]-4-quinazolinamine
    Molecular Weight:
    271.27
    Molecular Formula:
    C15H11F2N3
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 15 mg/ml with warming).
    Physical Properties:
    Tan solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $65.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Vacuolin-1 | Autophagy/PIKfyve inhibitor

    CAS:
    351986-85-1
    Catalog Number:
    10-5151
    View Product This product has multiple variants. The options may be chosen on the product page
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