PI-3K

  • IPI-549 | Selective PI3Kgamma inhibitor / Immuno-oncology agent

    CAS:
    1693758-51-8
    Catalog Number:
    10-4827
    Activity:
    Selective PI3K-gamma inhibitor / Immuno-oncology agent
    Chemical Name:
    (S)-2-Amino-N-[1-[8-[2-(1-methylpyrazol-4-yl)ethynyl]-1-oxo-2-phenylisoquinolin-3-yl]ethyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    Molecular Weight:
    629.68
    Molecular Formula:
    C30H24N8O2
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    Pale yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
  • LY 294002 | PI 3-Kinase inhibitor

    CAS:
    154447-36-6
    Catalog Number:
    10-2150
    Activity:
    PI 3-Kinase inhibitor
    Chemical Name:
    2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
    Molecular Weight:
    307.34
    Molecular Formula:
    C19H17NO3
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    Off-white to pale yellow solid
    Purity:
    >98%
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 4 months.
    Shipping Code:
    RT
    From $38.00
  • NVP-BEZ235 | PI3-K and mTOR inhibitor

    CAS:
    915019-65-7
    Catalog Number:
    10-2153
    Activity:
    PI 3-K and mTOR inhibitor
    Chemical Name:
    2-Methyl-2-{4-[3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl]phenyl}propanenitrile
    Molecular Weight:
    469.55
    Molecular Formula:
    C30H23N5O
    Solubility:
    Soluble in DMSO (up to 1 mg/ml with warming) or in DMF (up to 10 mg/ml, dissolves slowly, requires heating to 75¡C).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $40.00
  • PX-866 | PI3-K inhibitor

    CAS:
    502632-66-8
    Catalog Number:
    10-1315
    Activity:
    PI3-K inhibitor
    Molecular Weight:
    525.6
    Molecular Formula:
    C29H35NO8
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    Orange solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $60.00
  • Wortmannin | PI3K inhibitor

    CAS:
    19545-26-7
    Catalog Number:
    10-2115
    Activity:
    PI3K inhibitor
    Chemical Name:
    [(1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-6,11,16-trioxo-13,17-dioxapentacyclo[10.6.1.02,10.05,9.015,19]nonadeca-2(10),12(19),14-trien-3-yl] acetate
    Molecular Weight:
    428.44
    Molecular Formula:
    C23H24O8
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Dried aliquots evaporated from ethanol may be stored at -20° for several months. Solutions however are not stable and must be used within one working day. Note: Wortmannin decomposes fairly quickly in culture media
    Shipping Code:
    RT
    From $42.00
1 2 3