Caspases

  • Belnacasan | ICE/caspase-1 inhibitor

    CAS:
    273404-37-8
    Catalog Number:
    10-4399
    Activity:
    ICE/caspase-1 inhibitor
    Chemical Names:
    (S)-1-((S)-2-(4-Amino-3-chlorobenzamido)-3,3-dimethylbutanoyl)-N-((2R,3S)-2-ethoxy-5-oxotetrahydrofuran-3-yl)pyrrolidine-2-carboxamide; VX-765
    Molecular Weight:
    508.99
    Molecular Formula:
    C24H33ClN4O6
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Off-white to white solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $45.00
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  • Emricasan | pan-Caspase inhibitor

    CAS:
    254750-02-2
    Catalog Number:
    10-4280
    Activity:
    pan-Caspase inhibitor
    Chemical Names:
    (3S)-3-[[(2S)-2-[[2-(2-tert-butylanilino)-2-oxoacetyl]amino]propanoyl]amino]-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)pentanoic acid
    Alternate Name:
    IDN-6556; PF-03491390
    Molecular Weight:
    569.51
    Molecular Formula:
    C26H27F4N3O7
    Solubility:
    Soluble in DMSO (20 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $70.00
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  • PAC-1 | Procaspase activator

    CAS:
    315183-21-2
    Catalog Number:
    10-2979
    Activity:
    Procaspase activator
    Chemical Name:
    4-(Phenylmethyl)-1-piperazineacetic acid [[2-hydroxy-3-(2-propenyl)phenyl]-methylene]hydrazide
    Molecular Weight:
    392.49
    Molecular Formula:
    C23H28N4O2
    Solubility:
    Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 15 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol must be stored under inert gas at -80°C and will be stable for up to 2 months.
    Shipping Code:
    RT
    From $30.00
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  • Q-VD-OPh | Pan-specific caspase inhibitor

    CAS:
    1135695-98-5
    Catalog Number:
    10-2940
    Activity:
    Pan-specific caspase inhibitor
    Chemical Name:
    Quinolyl-valyl-aspartyl-[2,6-difluorophenoxy]methyl ketone
    Molecular Weight:
    513.49
    Molecular Formula:
    C26H25F2N3O6
    Solubility:
    Soluble in DMSO (up to 15 mg/ml)
    Physical Properties:
    White solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $80.00
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  • SM-164 | Smac mimetic

    CAS:
    957135-43-2
    Catalog Number:
    10-5464
    Activity:
    Smac mimetic
    Chemical Names:
    (3S,3′S,6S,6′S,10aS,10′aS)-N,N′-[1,4-phenylenebis[4,1-butanediyl-1H-1,2,3-triazole-1,4-diyl[(S)-phenylmethylene]]]bis[decahydro-6-[[(2S)-2-(methylamino)-1-oxopropyl]amino]-5-oxo-pyrrolo[1,2-a]azocine-3-carboxamide
    Molecular Weight:
    1121.45
    Molecular Formula:
    C62H84N14O6
    Solubility:
    Soluble in DMSO (50 mg/ml)
    Physical Properties:
    White to pale-yellow solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $190.00
    View Product This product has multiple variants. The options may be chosen on the product page
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