Highly-Selective Kinase Inhibitor Library

  • SNS-314 mesylate | Aurora kinase inhibitor

    CAS:
    1146618-41-8
    Catalog Number:
    10-4779
    Activity:
    Aurora kinase inhibitor
    Chemical Name:
    1-(3-Chlorophenyl)-3-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl]urea mesylate
    Molecular Weight:
    527.04
    Molecular Formula:
    C18H15ClN6OS2 • CH3SO3H
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $70.00
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  • TGX-221 | Potent and selective PI3Kß inhibitor

    CAS:
    663619-89-4
    Catalog Number:
    10-4783
    View Product This product has multiple variants. The options may be chosen on the product page
  • TH257 | Allosteric LIM kinase inhibitor

    CAS:
    2244678-29-1
    Catalog Number:
    10-4418
    Activity:
    Allosteric LIM kinase inhibitor
    Chemical Names:
    N-Butyl-4-[(phenylamino)sulfonyl]-N-(phenylmethyl)benzamide
    Molecular Weight:
    422.54
    Molecular Formula:
    C24H26N2O3S
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    White to off-white glassy solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Tofacitinib | JAK inhibitor

    CAS:
    477600-75-2
    Catalog Number:
    10-2177
    Activity:
    JAK inhibitor
    Alternate Names:
    Tasocitinib, CP-690550
    Molecular Weight:
    312.37
    Molecular Formula:
    C16H20N6O
    Solubility:
    Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 100 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    99% by HPLC and TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Trametinib | MEK inhibitor

    CAS:
    871700-17-3
    Catalog Number:
    10-4759
    Activity:
    MEK inhibitor
    Chemical Name:
    N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodophenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamide
    Alternate Names:
    GSK1120212
    Molecular Weight:
    615.39
    Molecular Formula:
    C26H23FIN5O4
    Solubility:
    Soluble in DMSO (up to 20 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $40.00
    View Product This product has multiple variants. The options may be chosen on the product page
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