Protease Inhibitors

  • Antipain 2HCl | Serine and cysteine protease inhibitor

    CAS:
    37682-72-7
    Catalog Number:
    10-2734
    Activity:
    Serine and cysteine protease inhibitor
    Chemical Name:
    (S)-1-Carboxy-2-phenylethyl]carbamoyl-L-arginyl-L-valyl-argininal, dihydrochloride
    Molecular Weight:
    677.62
    Molecular Formula:
    C27H44N10O6 • 2HCl
    Solubility:
    Soluble in Water (up to at least 10 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $35.00
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  • Belnacasan | ICE/caspase-1 inhibitor

    CAS:
    273404-37-8
    Catalog Number:
    10-4399
    Activity:
    ICE/caspase-1 inhibitor
    Chemical Names:
    (S)-1-((S)-2-(4-Amino-3-chlorobenzamido)-3,3-dimethylbutanoyl)-N-((2R,3S)-2-ethoxy-5-oxotetrahydrofuran-3-yl)pyrrolidine-2-carboxamide; VX-765
    Molecular Weight:
    508.99
    Molecular Formula:
    C24H33ClN4O6
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Off-white to white solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $45.00
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  • Bestatin HCl | Aminopeptidase inhibitor

    CAS:
    65391-42-6
    Catalog Number:
    10-1286
    Activity:
    Aminopeptidase inhibitor
    Chemical Name:
    [(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-L-leucine HCl
    Molecular Weight:
    344.84
    Molecular Formula:
    C16H24N2O4 HCl
    Solubility:
    Soluble in Water (up to 10 mg/ml). Also soluble in DMSO and Ethanol.
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO, distilled water, or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $40.00
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  • Chymostatin | Inhibitor of Chymotrypsin-like serine proteases

    CAS:
    9076-44-2
    Catalog Number:
    10-2722
    Activity:
    Inhibitor of chymotrypsin-like serine proteases
    Chemical Name:
    [(S)-1-Carboxy-2-phenylethyl]-carbamoyl-a-[2-amidohexahydro-4(S)-pyrimidyl]-(S)-glycyl-[A= Leu, B=Val, C=Ile]-phenylalaninal
    Molecular Weight:
    605.0 (ave.)
    Molecular Formula:
    C31H41N7O6
    Solubility:
    Soluble in DMSO (up to 20 mg/ml)
    Physical Properties:
    White or off-white solid
    Purity:
    96% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $98.00
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  • DAPT | gamma-secretase inhibitor

    CAS:
    208255-80-5
    Catalog Number:
    10-4514
    Activity:
    γ-secretase inhibitor
    Alternate Names:
    LY-374973
    Chemical Name:
    N-[N-(3,5-Difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester
    Molecular Weight:
    432.46
    Molecular Formula:
    C23H26F2N2O4
    Solubility:
    Soluble in DMSO (up to 18 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $55.00
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