DNA Damage/Repair

  • VE-821 | Potent and selective ATR inhibitor

    CAS:
    1232410-49-9
    Catalog Number:
    10-5589
    Activity:
    ATR inhibitor
    Chemical Names:
    3-Amino-6-[4-(methlsulfonyl)phenyl)-N-phenyl-2-pyrazinecarboxamide
    Molecular Weight:
    368.41
    Molecular Formula:
    C18H16N4O3S
    Solubility:
    Soluble in DMSO (40 mg/ml)
    Physical Properties:
    Beige solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $80.00
  • Veliparib 2HCl | PARP 1/2 inhibitor

    CAS:
    912445-05-7
    Catalog Number:
    10-2419
    Activity:
    PARP 1/2 inhibitor
    Chemical Names:
    2-[(2R)-2-Methyl-2-pyrrolidinyl]-1H-benzimidazole-7-carboxamide dihydrochloride
    Alternate Name:
    ABT-888
    Molecular Weight:
    317.22
    Molecular Formula:
    C13H16N4O·2HCl
    Solubility:
    Soluble in DMSO (30 mg/ml); water (40 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
  • YM-155 | Survivin inhibitor

    CAS:
    781661-94-7
    Catalog Number:
    10-1473
    Activity:
    Survivin inhibitor
    Alternate Names:
    Sepantronium bromide
    Chemical Name:
    1-(2-Methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazol-3-ium bromide
    Molecular Weight:
    443.3
    Molecular Formula:
    C20H19BrN4O3
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    Tan to yellow solid
    Purity:
    >98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $58.00
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