DNA Damage/Repair

  • RK-33 | DDX3 inhibitor

    CAS:
    1070773-09-9
    Catalog Number:
    10-4839
    Activity:
    DDX3 inhibitor
    Chemical Name:
    3,7-Bis(4-methoxybenzyl)-3,7-dihydro-1,3,4,6,7,9-hexaza-2H-cyclopenta[e]azulene-2-one
    Molecular Weight:
    428.44
    Molecular Formula:
    C23H20N6O3
    Solubility:
    Soluble in DMSO (up to 20 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $50.00
  • RS-1 | RAD51 activator / CRISPR enhancer

    CAS:
    312756-74-4
    Catalog Number:
    10-4099
    Activity:
    RAD51 activators / CRISPR enhancer
    Chemical Name:
    4-Bromo-N-(4-bromophenyl)-3-[[(phenylmethyl)amino]sulfonyl]benzamide
    Molecular Weight:
    524.23
    Molecular Formula:
    C20H16BrN2O3S
    Solubility:
    Soluble in DMSO (up to 30 mg/ml)
    Physical Properties:
    White solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
  • Rucaparib phosphate | PARP1 inhibitor

    CAS:
    459868-92-9
    Catalog Number:
    10-3321
    Activity:
    PARP1 inhibitor
    Chemical Name:
    8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2-ef][2]benzazepin-6-on
    Alternate Name:
    AG-14699; PF01367338
    Molecular Weight:
    421.36
    Molecular Formula:
    C19H18FN3O • H3PO4
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $70.00
  • SN-38 | DNA topoisomerase I inhibitor

    CAS:
    86639-52-3
    Catalog Number:
    10-2425
    Activity:
    DNA topoisomerase I inhibitor
    Chemical Name:
    7-Ethyl-10-hydroxycamptothecin
    Molecular Weight:
    392.41
    Molecular Formula:
    C22H20N2O5
    Solubility:
    Soluble in DMSO (up to 40 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $75.00
  • ß-Lapachone | Topoisomerase-1 inhibitor

    CAS:
    4707-32-8
    Catalog Number:
    10-2386
    Activity:
    Topoisomerase I inhibitor
    Chemical Name:
    3,4-Dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dione
    Alternate Name:
    NSC-26326
    Molecular Formula:
    C15H14O3
    Solubility:
    Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 15 mg/ml)
    Physical Properties:
    Orange solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $52.00
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