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Drug resistance

  • Ko-143 | BCRP inhibitor

    CAS:
    461054-93-3
    Catalog Number:
    10-1074
    Activity:
    BCRP inhibitor
    Chemical Name:
    (3S,6S,12aS)-1,2,3,4,6,7,12,12a-Octahydro-9-methoxy-6-(2-methylpropyl)-1,4-dioxopyrazino[1′,2′:1,6]pyrido [3,4-b]indole-3-propanoic acid 1,1-dimethylethyl ester
    Molecular Weight:
    469.59
    Molecular Formula:
    C26H35N3O5
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 50 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Protect from exposure to moisture. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $110.00
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  • MK-571 | Cys LT1 antagonist

    CAS:
    115104-28-4
    Catalog Number:
    10-1039
    Activity:
    Cys LT1 antagonist
    Alternate Names:
    L-660711
    Chemical Name:
    5-(3-(2-(7-Chloroquinolin-2-yl)ethenyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoic acid
    Molecular Weight:
    515.09
    Molecular Formula:
    C26H27ClN2O3S2
    Solubility:
    Soluble in DMSO (up to 50 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    95% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $60.00
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  • MTX-531 | Dual EGFR/PI3K inhibitor

    CAS:
    2791417-66-6
    Catalog Number:
    10-4802
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  • Napabucasin | STAT3 inhibitor / Cancer cell stemness inhibitor

    CAS:
    83280-65-3
    Catalog Number:
    10-3442
    Activity:
    STAT3 inhibitor / Cancer cell stemness inhibitor
    Chemical Name:
    2-Acetylnsphtho[2,3-b]furan-4,9-dione
    Alternate Names:
    BBI608
    Molecular Weight:
    240.21
    Molecular Formula:
    C14H8O4
    Solubility:
    Soluble in DMSO (up to 20 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $58.00
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  • NGI-1 chemical structure

    NGI-1 | Oligosaccharyltransferase (OST) inhibitor

    CAS:
    790702-57-7
    Catalog Number:
    10-4291
    Activity:
    Oligosaccharyltransferase (OST) inhibitor
    Chemical Name:
    5-(Dimethylsulfamoyl)-N-(5-methyl-1,3-thiazol-2-yl)-2-(pyrrolidin-1-yl)benzamide
    Alternate Names:
    ML414
    Molecular Weight:
    394.51
    Molecular Formula:
    C17H22N4O3S2
    Solubility:
    Soluble in DMSO (up to 5 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $65.00
    View Product This product has multiple variants. The options may be chosen on the product page
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