Drug resistance Archives | Page 3 of 5

Napabucasin | STAT3 inhibitor / Cancer cell stemness inhibitor

CAS:

83280-65-3

Catalog Number:

10-3442

Activity:

STAT3 inhibitor / Cancer cell stemness inhibitor

Chemical Name:

2-Acetylnsphtho[2,3-b]furan-4,9-dione

Alternate Names:

BBI608

Molecular Weight:

240.21

Molecular Formula:

C₁₄H₈O₄

Solubility:

Soluble in DMSO (up to 20 mg/ml)

Physical Properties:

Yellow solid

Purity:

98% by TLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $58.00
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NGI-1 | Oligosaccharyltransferase (OST) inhibitor

CAS:

790702-57-7

Catalog Number:

10-4291

Activity:

Oligosaccharyltransferase (OST) inhibitor

Chemical Name:

5-(Dimethylsulfamoyl)-N-(5-methyl-1,3-thiazol-2-yl)-2-(pyrrolidin-1-yl)benzamide

Alternate Names:

ML414

Molecular Weight:

394.51

Molecular Formula:

C₁₇H₂₂N₄O₃S₂

Solubility:

Soluble in DMSO (up to 5 mg/ml)

Physical Properties:

White solid

Purity:

98% by TLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Shipping Code:

RT

From $55.00
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Nicardipine HCl | L-type Ca channel blocker / MDR inhibitor

CAS:

54527-84-3

Catalog Number:

10-1201

Activity:

L-type Ca channel blocker / MDR inhibitor

Chemical Name:

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)methyl-2-[methyl(phenylmethyl)amino]-3,5-pyridinedicarboxylic acid methyl ester hydrochloride

Molecular Weight:

515.99

Molecular Formula:

C₂₆H₂₉N₃O₆·HCl

Solubility:

Soluble in Ethanol (up to 20 mg/ml) or in Water (up to 5 mg/ml).

Physical Properties:

Pale-yellow solid

Purity:

98% by TLC
NMR (Conforms)

Storage Temperature:

RT

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in distilled water or ethanol may be stored at -20°C for up to 1 month.

Shipping Code:

RT

From $30.00
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Panobinostat | HDAC inhibitor

CAS:

404950-80-7

Catalog Number:

10-2157

Activity:

HDAC inhibitor

Alternate Names:

LBH-589

Chemical Name:

(E)-N-Hydroxy-3-(4-((2-(2-methyl-1H-indol-3-yl)ethylamino)methyl)phenyl)acrylamide

Molecular Weight:

349.44

Molecular Formula:

C₂₁H₂₃N₃O₂

Solubility:

Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 5 mg/ml with warming).

Physical Properties:

Off-white solid

Purity:

98% by TLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.

Shipping Code:

RT

From $40.00
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Quizartinib | Selective FLT3 Inhibitor

CAS:
950769-58-1

Catalog Number:

10-4813

Activity:

Selective FLT3 inhibitor

Chemical Name:

1-(5-(t-Butyl)isoxazol-3-yl)-3-(4-(7-(2-morpholinoethoxy)benzo[d]imidazo[2,1-b]thiazol-2-yl)phenyl)urea

Alternate Names:

AC220

Molecular Weight:

560.67

Molecular Formula:

C₂₉H₃₂N₆O₄S

Solubility:

Soluble in DMSO (up to at least 25 mg/ml)

Physical Properties:

Off-white solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Shipping Code:

RT

From $50.00
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Drug resistance

Napabucasin | STAT3 inhibitor / Cancer cell stemness inhibitor

NGI-1 | Oligosaccharyltransferase (OST) inhibitor

Nicardipine HCl | L-type Ca channel blocker / MDR inhibitor

Panobinostat | HDAC inhibitor

Quizartinib | Selective FLT3 Inhibitor

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

Drug resistance

Napabucasin | STAT3 inhibitor / Cancer cell stemness inhibitor

NGI-1 | Oligosaccharyltransferase (OST) inhibitor

Nicardipine HCl | L-type Ca channel blocker / MDR inhibitor

Panobinostat | HDAC inhibitor

Quizartinib | Selective FLT3 Inhibitor

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules Plymouth Meeting, PA USA1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21