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Growth factors

  • Cabozantinib | Met and VEGFR2 inhibitor

    CAS:
    849217-68-1
    Catalog Number:
    10-3231
    Activity:
    Met and VEGFR2 inhibitor
    Chemical Name:
    N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
    Alternate Names:
    XL-184; BMS-907351; Carbozantinib
    Molecular Weight:
    501.51
    Molecular Formula:
    C28H24FN3O5
    Solubility:
    Soluble in DMSO
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $70.00
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  • Crenolanib | PDGFR and FLT3 inhibitor

    CAS:
    670220-88-9
    Catalog Number:
    10-4782
    Activity:
    PDGFR and FLT3 inhibitor
    Chemical Name:
    1-[2-[5-[(3-Methyloxetan-3-yl)methoxy]benzimidazole-1-yl]quinoline-8-yl]piperidin-4-amine
    Alternate Name:
    CP-868,596
    Molecular Weight:
    443.55
    Molecular Formula:
    C26H29N5O2
    Solubility:
    Soluble in DMSO (up to 15 mg/ml) or in Ethanol (up to 10 mg/ml).
    Physical Properties:
    White solid
    Purity:
    >97% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $60.00
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  • Erlotinib HCl | EGFR Kinase inhibitor

    CAS:
    183319-69-9
    Catalog Number:
    10-2135
    Activity:
    EGFR Kinase inhibitor
    Chemical Name:
    N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride
    Molecular Weight:
    429.91
    Molecular Formula:
    C22H23N3O4 HCl
    Solubility:
    Soluble in DMSO (up to 18 mg/ml with warming).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $35.00
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  • Fruquintinib | Potent and selective inhibitor of VEGFR kinase

    CAS:
    1194506-26-7
    Catalog Number:
    10-4784
    Activity:
    Potent and selective inhibitor of VEGFR kinase
    Chemical Name:
    6-(6,7-Dimethoxyquinazolin-4-yl)oxy-N,2-dimethyl-1-benzofuran-3-carboxamide
    Alternate Name:
    HMPL-013
    Molecular Weight:
    393.40
    Molecular Formula:
    C21H<sub19< sub=””>N3O4</sub19<>
    Solubility:
    Soluble in DMSO (up to 5 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $60.00
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  • Gefitinib | EGFR kinase inhibitor

    CAS:
    184475-35-2
    Catalog Number:
    10-1148
    Activity:
    EGFR-Kinase inhibitor
    Alternate Names:
    ZD1839, Iressa
    Chemical Name:
    N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
    Molecular Weight:
    446.91
    Molecular Formula:
    C22H24ClFN4O3
    Solubility:
    Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 4 mg/ml).
    Physical Properties:
    Tan solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $30.00
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Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

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