Aurora kinase

  • Alisertib | Potent and selective inhibitor of Aurora A / Destabilizes Myc

    CAS:
    1028486-01-2
    Catalog Number:
    10-4124
    Activity:
    Potent and selective inhibitor of Aurora A / Destabilizes Myc
    Chemical Name:
    4-{[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino}-2-methoxybenzoic acid
    Alternate Names:
    MLN8237
    Molecular Weight:
    518.92
    Molecular Formula:
    C27H20ClFN4O4
    Solubility:
    Soluble in DMSO (up to 5 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
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  • AZD1152-HQPA | Aurora B kinase inhibitor

    CAS:
    722544-51-6
    Catalog Number:
    10-4804
    Activity:
    Aurora B kinase inhibitor
    Chemical Name:
    3-[[7-[3-[Ethyl(2-hydroxyethyl)amino]propoxy]-4-quinazolinyl]amino-N-(3-fluorophenyl)-1H-pyrazole-5-acetamide
    Alternate Name:
    Barasertib-HQPA; AZD2811
    Molecular Weight:
    507.56
    Molecular Formula:
    C26H30FN7O3
    Solubility:
    Soluble in DMSO (up to 15 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • SNS-314 mesylate | Aurora kinase inhibitor

    CAS:
    1146618-41-8
    Catalog Number:
    10-4779
    Activity:
    Aurora kinase inhibitor
    Chemical Name:
    1-(3-Chlorophenyl)-3-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl]urea mesylate
    Molecular Weight:
    527.04
    Molecular Formula:
    C18H15ClN6OS2 • CH3SO3H
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $70.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Tozasertib | Aurora kinase inhibitor

    CAS:
    639089-54-6
    Catalog Number:
    10-2178
    Activity:
    Aurora kinase inhibitor
    Alternate Names:
    VX-680, MK-0457
    Molecular Weight:
    464.59
    Molecular Formula:
    C23H28N8OS
    Solubility:
    Soluble in DMSO (up to 100 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • ZM-447439 | Aurora B kinase inhibitor

    CAS:
    331771-20-1
    Catalog Number:
    10-1037
    Activity:
    Aurora B kinase inhibitor
    Chemical Name:
    N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide
    Molecular Weight:
    513.59
    Molecular Formula:
    C29H31N5O4
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase  as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $52.00
    View Product This product has multiple variants. The options may be chosen on the product page

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