Cyclin/CDK

  • Ribociclib | CDK4/6 inhibitor

    CAS:
    1211441-98-3
    Catalog Number:
    10-4807
    Activity:
    CDK4/6 inhibitor
    Chemical Name:
    7-Cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
    Alternate Names:
    LEE011
    Molecular Weight:
    434.54
    Molecular Formula:
    C23H30N8O3
    Solubility:
    Soluble in DMSO (up to 10 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $60.00
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  • RO-3306 | Selective CDK1 inhibitor

    CAS:
    872573-93-8
    Catalog Number:
    10-4126
    Activity:
    Selective CDK1 inhibitor
    Chemical Name:
    5-(6-Quinolinylmethylene)-2-[(2-thienylmethyl)amino]-4(5H)-thiazolone
    Molecular Weight:
    351.45
    Molecular Formula:
    C18H13N3OS2
    Solubility:
    Soluble in DMSO (up to 15 mg/ml)
    Physical Properties:
    Off-white or pale yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $65.00
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  • Roscovitine | p34/cdc2 inhibitor

    CAS:
    186692-46-6
    Catalog Number:
    10-1332
    Activity:
    p34/cdc2 inhibitor
    Chemical Name:
    (R)-2-((6-(Benzylamino)-9-isopropyl-9H-purin-2-yl)amino)butan-1-ol
    Molecular Weight:
    354.46
    Molecular Formula:
    C19H26N6O
    Solubility:
    Soluble in DMSO (up to 10 mg/ml, with warming) or in Ethanol (up to 10 mg/ml).
    Physical Properties:
    White solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $45.00
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  • SU9516 | pan-specific CDK inhibitor

    CAS:
    SU9516
    Catalog Number:
    10-5705
    Activity:
    pan-specific CDK inhibitor
    Chemical Names:
    (Z)-1,3-Dihydro-3-(1H-imidazol-4-ylmethylene)-5-methoxy-2H-2-one
    Molecular Weight:
    241.25
    Molecular Formula:
    C13H11N3O2
    Solubility:
    Soluble in DMSO (25 mg/ml)
    Physical Properties:
    Orange solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $75.00
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  • THZ1 | Potent and selective CDK7 inhibitor

    CAS:
    1604810-83-4
    Catalog Number:
    10-4120
    Activity:
    Potent and selective CDK7 inhibitor
    Chemical Name:
    (E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-enamido)benzamide
    Molecular Weight:
    566.05
    Molecular Formula:
    C31H28ClN7O2
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    Tan solid
    Purity:
    97% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $80.00
    View Product This product has multiple variants. The options may be chosen on the product page
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