Ribociclib | CDK4/6 inhibitor
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 10 mg | $60.00 | ||
| 50 mg | $180.00 |
Ribociclib (1211441-98-3) is a clinically useful, potent, and specific CDK4/6 inhibitor.1,2,3 It was recently approved for use in HR+, HER2- metastatic breast cancer.
References/Citations:
1) Rader et al. (2013), Dual CDK4/6 inhibition induces cell-cycle arrest and senescence in neuroblastoma; Clin. Cancer Res. 19 6173
2) Kim et al. (2013), LEE011: an orally bioavailable, selective small-molecule inhibitor of CDK4/6 – reactivating Rb in cancer; Mol. Cancer Ther. 12 PR02
3) Tripathy et al. (2017), Ribociclib(LEE011): mechanism of action and clinical impact of this selective cyclin-dependent kinase 4/6 inhibitor in various solid tumors; Clin. Cancer Res. March 28, 201
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Ribociclib (1211441-98-3) is a clinically useful, potent, and specific CDK4/6 inhibitor.1,2,3 It was recently approved for use in HR+, HER2- metastatic breast cancer.
References/Citations:
1) Rader et al. (2013), Dual CDK4/6 inhibition induces cell-cycle arrest and senescence in neuroblastoma; Clin. Cancer Res. 19 6173
2) Kim et al. (2013), LEE011: an orally bioavailable, selective small-molecule inhibitor of CDK4/6 – reactivating Rb in cancer; Mol. Cancer Ther. 12 PR02
3) Tripathy et al. (2017), Ribociclib(LEE011): mechanism of action and clinical impact of this selective cyclin-dependent kinase 4/6 inhibitor in various solid tumors; Clin. Cancer Res. March 28, 201
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Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21
Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21
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