Inhibitors

  • Baicalein | Inhibitor of protein tyrosine kinase in leukemia cells

    CAS:
    491-67-8
    Catalog Number:
    10-2773
    Activity:
    Inhibitor of protein tyrosine kinase in leukemia (CEM cells)
    Chemical Name:
    5,6,7-Trihydroxyflavone
    Molecular Weight:
    270.24
    Molecular Formula:
    C15H10O5
    Physical Properties:
    Yellow or yellow-green solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week.
    Shipping Code:
    RT
    From $40.00
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  • BO-264 | TACC3 inhibitor

    CAS:
    2408648-20-2
    Catalog Number:
    10-4685
    Activity:
    TACC3 inhibitor
    Chemical Names:
    3-(4-Methoxyphenyl)-N-(2-morpholin-4-ylpyrimidin-4-yl)-1,2-oxazol-5-amine
    Molecular Weight:
    353.38
    Molecular Formula:
    C18H19N5O3
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    99% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $65.00
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  • CFM-4 | CARP-1 mimetic

    CAS:
    331458-02-7
    Catalog Number:
    10-1493
    Activity:
    Carp-1 mimetic
    Chemical Name:
    1-[(2-Chlorophenyl)methyl]-5′-phenyl-spiro[3H-indole-3,2′(3’H)-[1,3,4]thiadiazol]-2(1H)-one
    Molecular Weight:
    405.90
    Molecular Formula:
    C22H16ClN3OS
    Solubility:
    Soluble in DMSO (greater than 25 mg/ml)
    Physical Properties:
    Tan solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $70.00
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  • CI-994 | HDAC Inhibitor

    CAS:
    112522-64-2
    Catalog Number:
    10-2125
    Activity:
    HDAC inhibitor
    Chemical Name:
    4-(Acetylamino)-N-(2-aminophenyl)benzamide
    Alternate Names:
    Tacedinaline; PD-123654; N-acetyl-dinaline; GOE-5549
    Molecular Weight:
    269.30
    Molecular Formula:
    C15H15N3O2
    Solubility:
    Soluble in DMSO (up to 25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $38.00
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  • Crizotinib | c-MET and ALK inhibitor

    CAS:
    877399-52-5
    Catalog Number:
    10-2626
    Activity:
    c-MET and ALK inhibitor
    Chemical Name:
    3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-pyridinamine
    Alternate Names:
    PF-02341066, PF-1066
    Molecular Weight:
    450.34
    Molecular Formula:
    C21H22Cl2FN5O
    Solubility:
    Soluble in DMSO (up to 25 mg/ml with warming) or in Ethanol (up to 25 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $80.00
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