Other Inflammation

  • I-BET762 | BET Bromodomain inhibitor / Suppresses Myc transcription

    CAS:
    1260907-17-2
    Catalog Number:
    10-4122
    Activity:
    BET Bromodomain inhibitor / Supresses Myc transcription
    Chemical Name:
    (4S)- 6-(4-Chlorophenyl)-N-ethyl-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-4-acetamide
    Alternate Names:
    GSK525762
    Molecular Weight:
    423.90
    Molecular Formula:
    C22H22ClN5O2
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to at least 25 mg/ml)
    Physical Properties:
    Tan solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $80.00
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  • Ibudilast | Neuroinflammation inhibitor

    CAS:
    50847-11-5
    Catalog Number:
    10-2236
    Activity:
    Neuroinflammation inhibitor
    Chemical Name:
    3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine
    Alternate Names:
    2-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridine-3-yl 1-propanone; KC-404; AV411
    Molecular Weight:
    230.31
    Molecular Formula:
    C14H18N2O
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or Ethanol (up to 20 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $40.00
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  • JTE-607 | mRNA processing inhibitor

    CAS:
    188791-09-5
    Catalog Number:
    10-4842
    Activity:
    mRNA processing inhibitor
    Chemical Name:
    Ethyl (2S)-2-[[3,5-Dichloro-2-hydroxy-4-[2-(4-methylpiperazin-1-yl)ethoxy]benzoyl]amino]-3-phenylpropanoate dihydrochloride
    Molecular Weight:
    597.36
    Molecular Formula:
    C25H31Cl2N3O5 • 2HCl
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    Off-white to pale yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20° (des.)
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $60.00
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  • Laquinimod | Immunomodulator

    CAS:
    248281-84-7
    Catalog Number:
    10-4971
    Activity:
    Immunomodulator
    Chemical Names:
    5-Chloro-N-ethyl-4-hydroxy-1-methyl-2-oxo-N-phenylquinoline-3-carboxamide
    Alternate Name:
    ABR-215062
    Molecular Weight:
    356.81
    Molecular Formula:
    C19H17ClN2O3
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $30.00
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  • Methotrexate | Dihydrofolate reductase inhibitor

    CAS:
    133073-73-1
    Catalog Number:
    10-1260
    Activity:
    Dihydrofolate reductase inhibitor
    Chemical Names:
    N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid; Amethopterin; CL-14377; NSC740
    Molecular Weight:
    683.63
    Molecular Formula:
    C20H22N8O5·XH2O
    Solubility:
    Soluble in DMSO (45 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page
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