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Necroptosis

  • Matrine | Induces RIP3-dependent necroptosis

    CAS:
    519-02-8
    Catalog Number:
    10-4612
    Activity:
    Induces RIP3-dependent necroptosis
    Chemical Name:
    (7aS,13aR,13bR,13cS)-Dodecahydro-1H,5H,10H-dipyrido[2,1-f:3’,2’,1’-ij][1,6]napthyridin-10-one
    Source:
    Isolated from Sophora flavescens
    Molecular Weight:
    248.36
    Molecular Formula:
    C15H24N2O
    Solubility:
    Soluble in Water (up to 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $30.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Necrostatin-1 | Inhibits necroptosis

    CAS:
    4311-88-0
    Catalog Number:
    10-1162
    Activity:
    Inhibits necroptosis
    Chemical Name:
    5-(1H-Indol-3-ylmethyl)-3-methyl-2-thioxo-4-Imidazolidinone
    Molecular Weight:
    259.33
    Molecular Formula:
    C13H13N3OS
    Solubility:
    Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 5 mg/ml).
    Physical Properties:
    Pale yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied.  Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $55.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Necrostatin-34 chemical structure Focus Biomolecules

    Necrostatin-34 | RIP1 kinase inhibitor

    CAS:
    375835-43-1
    Catalog Number:
    10-4684
    View Product This product has multiple variants. The options may be chosen on the product page

  • Necrosulfonamide | Necroptosis inhibitor / MLKL inhibitor

    CAS:
    1360614-48-7
    Catalog Number:
    10-4860
    Activity:
    Necroptosis inhibitor / MLKL inhibitor
    Chemical Name:
    (2E)-N-[4-[[(3-Methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenamide
    Molecular Weight:
    461.47
    Molecular Formula:
    C18H15N5O6S2
    Solubility:
    Soluble in DMSO (up to 10 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $45.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • RIPA-56 | RIP1 kinase inhibitor

    CAS:
    1956370-21-0
    Catalog Number:
    10-4611
    Activity:
    RIP1 kinase inhibitor
    Chemical Name:
    N-Benzyl-N-hydroxy-2,2-dimethylbutanamide
    Molecular Weight:
    221.30
    Molecular Formula:
    C13H19NO2
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 50 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $55.00
    View Product This product has multiple variants. The options may be chosen on the product page
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Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

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