Wnt/ß-Catenin

  • IM-12 | GSK-3ß inhibitor

    CAS:
    1129669-05-1
    Catalog Number:
    10-5125
    Activity:
    GSK-3ß inhibitor
    Chemical Names:
    3-(4-Fluorophenylethylamino)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
    Molecular Weight:
    377.41
    Molecular Formula:
    C22H20FN3O2
    Solubility:
    Soluble in DMSO (50 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $52.00
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  • IWP-2 | Porcn inhibitor: Wnt/Beta-catenin pathway inhibitor

    CAS:
    686770-61-6
    Catalog Number:
    10-1308
    Activity:
    Porcn inhibitor: Wnt/β-catenin pathway inhibitor
    Chemical Name:
    N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide
    Molecular Weight:
    466.61
    Molecular Formula:
    C22H18N4O2S3
    Solubility:
    Soluble in DMSO (up to 5 mg/ml, with warming).
    Physical Properties:
    Beige solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $55.00
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  • IWR-1 endo | Wnt signaling inhibitor

    CAS:
    1127442-82-3
    Catalog Number:
    10-5081
    Activity:
    Wnt signaling inhibitor
    Molecular Weight:
    409.44
    Molecular Formula:
    C25H19N3O2
    Solubility:
    Soluble in DMSO (up to 10 mg/ml)
    Physical Properties:
    Off-white or yellow solid
    Purity:
    98% by TLC/HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
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  • KY-02111 | Wnt pathway inhibitor

    CAS:
    1118807-13-8
    Catalog Number:
    10-1437
    Activity:
    Wnt pathway inhibitor
    Chemical Name:
    N-(6-Chloro-2-benzothiazolyl)-3,4-dimethoxybenzenepropanamide
    Molecular Weight:
    376.86
    Molecular Formula:
    C18H17ClN2O3S
    Solubility:
    Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 5 mg/ml with warming).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $55.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Wnt-C59 | Porcupine Inhibitor

    CAS:
    1243243-89-1
    Catalog Number:
    10-4605
    Activity:
    Porcupine Inhibitor
    Chemical Name:
    4-(2-Methyl-4-pyridinyl)-N-[4-(3-pyridinyl)phenyl]benzeneacetamide
    Molecular Weight:
    379.46
    Molecular Formula:
    C25H21N3O
    Solubility:
    Soluble in DMSO (up to 7 mg/ml) or in Ethanol (up to 6 mg/mL)
    Physical Properties:
    Tan solid
    Purity:
    >98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page
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