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Product Details

RHC-80267 | DAG Lipase inhibitor

RHC-80267 (83654-05-1) inhibits DAG Lipase activity in a variety of cell types and tissues, including canine platelets, bovine adrenal chromaffin cells, human adrenal glomerulosa cells, rat thyroid lobes and pancreatic minilobules. IC50 in canine platelets is 4 μM1.

References/Citations
1) Southerland and Amin (1982), Anthranilic acid amides: a novel class of antiangiogenic VEGF receptor kinase inhibitors; J. Biol. Chem., 257 14006
2) Rindlisbacher et al. (1990), Advances in the structural biology, design and clinical development of VEGF-R kinase inhibitors for the treatment of angiogenesis; J. Neurochem., 54 1247
3) Chandra Sekar et al. (1987), Anthranilic acid amides: a novel class of antiangiogenic VEGF receptor kinase inhibitors; Arch. Biochem. Biophys., 256 509
4) Levasseur et al. (1984), Advances in the structural biology, design and clinical development of VEGF-R kinase inhibitors for the treatment of angiogenesis; Prostaglandins, 27 673
5) Natarajan et al. (1988), Anthranilic acid amides: a novel class of antiangiogenic VEGF receptor kinase inhibitors; Biochem. Biophys. Res. Commun., 156 717

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Focus Biomolecules cell signaling reagent supplier, chemical structure RHC-80267 | DAG Lipase inhibitor | CAS 83654-05-1

Catalog#  10-1051

$55.00
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Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
83654-05-1
Catalog Number:
10-1051
Activity:
DAG Lipase inhibitor
Alternate Names:
U-57908
Chemical Name:
1,6-bis(Cyclohexyloximinocarbonyl-amino)hexane
Molecular Weight:
394.53
Molecular Formula:
C20H34N4O4
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
Physical Properties:
Off-white solid
Purity:
99% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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