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Product Details

Ritonavir | HIV1/2 protease inhibitor

Ritonavir (155213-67-5) is a clinically useful HIV-1/HIV-2 protease inhibitor.1 Potent inhibitor of cytochrome P450 3A4.2,3

References/Citations
1) Lea and Faulds (2018) Ritonavir; Drugs 52 541
2) Koudriakova et al. (1998) Metabolism of the Human Immunodeficiency Virus Protease Inhibitors Indinavir and Ritonavir by Human Intestinal Microsomes and Expressed Cytochrome P4503A4/3A5: Mechanism-Based Inactivation of Cytochrome P3503A by Ritonavir; Drug Metab. Dispos. 26 552
3) Rock et al. (2014) Characterization of Ritonavir-Mediated Inactivation of Cytochrome P450 3A4; Mol. Pharmacol. 86 665

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Catalog#  10-4484-0010

$40.00
Quantity
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CAS:
155213-67-5
Catalog Number:
10-4484
Activity:
HIV 1/2 protease inhibitor
Chemical Name:
1,3-Thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[[(2S)-3-methyl-2-[[methyl-2-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]carbamoyl]amino]butanoyl]amino]-1,6-diphenylhexan-2-yl]carbamate
Molecular Weight:
720.95
Molecular Formula:
C37H48N5O5S2
Solubility:
Soluble in DMSO (up to 12 mg/ml with warming) or in Ethanol (up to 5 mg/ml).
Physical Properties:
White solid
Purity:
98% by HPLC
Storage Temperature:
-20°C
Stability:
Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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