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Product Details

RO 20-1724 | PDE4 inhibitor

RO 20-1724 (29925-17-5) is a selective inhibitor of cAMP-specific phosphodiesterase (PDE4), IC50 = 0.2 μM. Displays anti-inflammatory activity. Cell permeable

References/Citations
1) Soderling et al. (1998), Cloning and characterization of a cAMP-specific cyclic nucleotide phosphodiesterase; Proc. Natl. Acad. Sci. USA, 95 8991
2) Nicholson et al. (1991), Differential modulation of tissue function and therapeutic potential of selective inhibitors of cyclic nucleotide phosphodiesterase isoenzymes; Trends Pharmacol. Sci., 12 19

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RO 20-1724 | 28825-17-5 | Structure | Supplier

Catalog#  10-1014

$45.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
29925-17-5
Catalog Number:
10-1014
Activity:
PDE4 inhibitor
Chemical Name:
4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone
Molecular Weight:
278.35
Molecular Formula:
C15H22N2O3
Solubility:
Soluble in DMSO (up to 200 mg/ml) or in Ethanol (up to 40 mg/ml).
Physical Properties:
White solid
Purity:
99% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 6 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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