TPEN | Intracellular Zn2+ chelator

CAS:
16858-02-9
Catalog Number:
10-1228
Activity:
Intracellular Zn2+ chelator
Chemical Name:
N,N,N’,N’-Tetrakis(2-pyridylmethyl)ethylenediamine
Molecular Weight:
424.54
Molecular Formula:
C26H28N6
Solubility:
Soluble in DMSO (up to 10 mg/ml).
Physical Properties:
Off-white or tan solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Available Options

size :PriceQuantity 
100 mg$86.00
500 mg$344.00

TPEN (16858-02-9) is a cell permeable metal chelator. Frequently used to study effects of zinc depletion on cellular processes.1,2

References/Citations:

1) Chimienti et al. (2001) Role of cellular zinc in programmed cell death: temporal relationship between zinc depletion, activation of caspases and cleavage of Sp family transcription factors; Biochem. Pharmacol. 62 51
2) Meplan et al. (2000) Metalloregulation of the tumor suppressor protein p53: zinc mediates the renaturation of p53 after exposure to metal chelators in vitro and in intact cells; Oncogene 19 5227

CAS:
16858-02-9
Catalog Number:
10-1228
Activity:
Intracellular Zn2+ chelator
Chemical Name:
N,N,N’,N’-Tetrakis(2-pyridylmethyl)ethylenediamine
Molecular Weight:
424.54
Molecular Formula:
C26H28N6
Solubility:
Soluble in DMSO (up to 10 mg/ml).
Physical Properties:
Off-white or tan solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee