Metals and biological systems
Many enzymes and systems depend on metal ions, such as zinc, iron, and copper, for proper function. These include proteases (active site function), hemoglobins (carrying oxygen), cytochromes (electron transfer), free radical control, and metal ion storage. Chelators sequester metal ions, offering a way to control or block these functions, which can be useful in infectious disease, wound healing, and heavy metal poisoning, and research in metal-dependent processes such as ferroptosis, cuproptosis, and oxidative stress.
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Bleomycin sulfate | Induces double strand DNA breaks
From $75.00CAS:9041-93-4Catalog Number:10-2623Activity:Fibrosis-inducing agentSource:From Streptomyces verticillusMolecular Weight:1512.62Molecular Formula:C55H85N17O25S4Solubility:Soluble in Water (up to 20 mg/ml)Physical Properties:White or off-white solidPurity:Contains a mixture of A2 (~70%) and B2 (~30%) forms95% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from the date of purchase. Solutions in distilled water may be stored at -20°C for up to 3 months.Shipping Code:RT -
Cisplatin | Anticancer agent
From $50.00CAS:15663-27-1Catalog Number:10-2204Activity:Anticancer agentChemical Name:Cis-DiaminodichloroplatinumAlternate Names:CDDP; cis-Diamineplatinum(II) dichlorideMolecular Weight:300.05Molecular Formula:Cl2H4N2PtSolubility:Soluble in Water (up to 2.5 mg/ml with warming)Physical Properties:Yellow solidPurity:98% by HPLC
Elemental Analysis (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in distilled water are not stable and must be used within 1 working day. do not store solutions.Shipping Code:RT -
Deferasirox | Iron Chelator
From $50.00CAS:201530-41-8Catalog Number:10-4949Activity:Iron chelatorChemical Names:4-[3,5-bis(2-Hydroxyphenyl)-1,2,4-triazol-1-yl]benzoic acidAlternate Name:ICL670Molecular Weight:373.36Molecular Formula:C21H15N3O4Solubility:Soluble in DMSO (10 mg/ml)Physical Properties:Off-white to white solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
Deferiprone | Iron Chelator
$20.00CAS:30652-11-0Catalog Number:10-4950Activity:Iron chelatorChemical Name:3-Hydroxy-1,2-dimethylpyrid-4-oneAlternate Name:FerriproxMolecular Weight:139.15Molecular Formula:C7H9NO2Solubility:Soluble in Water (up to 5 mg/ml with warming).Physical Properties:White solidPurity:98% by TLCNMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions are not stable and must be prepared fresh daily.Shipping Code:RT -
Divin | Divisome assembly inhibitor
From $75.00CAS:1443321-11-6Catalog Number:10-4105Activity:Divisome assembly inhibitorChemical Name:N’-[(E)-(2-Hydroxynaphthalen-1-yl)methylidene]-3-(2-methyl-1H-benzimidazol-1-yl)propanehydrazideMolecular Weight:372.42Molecular Formula:C22H20N4O2Solubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:Pale yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Dp44mT | Metal chelator
From $25.00CAS:152095-12-0Catalog Number:10-4951Activity:Metal chelatorChemical Name:3-(Dipyridin-2-ylmethylideneamino)-1,1-dimethylthioureaMolecular Weight:285.37Molecular Formula:C14H15N5SSolubility:Soluble in DMSO (up to at least 25 mg/ml).Physical Properties:Orange solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may ne stored at -20°C for 1 month.Shipping Code:RT
