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Safracin B | Anticancer agent

CAS:
87578-99-2
Catalog Number:
10-3208
Activity:
Anticancer agent
Source:
Produced by Pseudomonas fluorescens
Molecular Weight:
540.61
Molecular Formula:
C28H36N4O7
Solubility:
Soluble in DMSO (up to 20 mg/ml)
Physical Properties:
Yellow-green solid
Purity:
90% by HPLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Safracin B (87578-99-2) is a novel antibiotic of the saframycin family produced by Pseudomonas fluorescens.1 Safracin B displays antitumor activity against L1210 and P388 leukemias and B16 melanoma. Compared with safracin A, the toxic and effective doses were much lower. Safracin B also prolonged the life of tumor-bearing mice to a greater extent than safracin A.2

References/Citations:

1) Ikeda et al. (1983), Safracins, new antitumor antibiotics. I. Producing organism, fermentation and isolation; J. Antibiot. Tokyo, 36 1279
2) Okumoto et al. (1985), Activity of safracins A and B, heterocyclic quinone antibiotics, on experimental tumors in mice; J. Antibiot.Tokyo, 38 767

Safracin B | Anticancer agent is also available in the Cellular Metabolism Library.
CAS:
87578-99-2
Catalog Number:
10-3208
Activity:
Anticancer agent
Source:
Produced by Pseudomonas fluorescens
Molecular Weight:
540.61
Molecular Formula:
C28H36N4O7
Solubility:
Soluble in DMSO (up to 20 mg/ml)
Physical Properties:
Yellow-green solid
Purity:
90% by HPLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

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