SB-405483 | Allosteric cereblon ligand

SB-405483 chemical structure

Available Options

Size:PriceQuantity 
1 mg$45.00
5mg$175.00

SB-405483 binds to an allosteric site on cereblon (CRBN) enhancing the binding of other cereblon ligands and altering their degradation profiles.

Referencesw/Citations:

  1. Dippon et al. (2026), Identification of an allosteric site on the E3 ligase adapter cereblon; Nature 651 482
Allosteric cereblon ligand, SB-405483, SB-405483 supplier, SB405483

Safety Data Sheet:

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee